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KMID : 0380020140290040271
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Korean Journal of Biotechnology and Bioengineering
2014 Volume.29 No. 4 p.271 ~ p.277
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Antioxidant Activity of the Seagrass Zostera japonica
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Kwak Myoung-Kuk
Kim Da-Seul
Oh Kwang-Suk
Seo Young-Wan
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Abstract
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In this study, crude extract of the seagrass Zostera japonica, and its solvent-partitioned fractions were evaluated for their antioxidant activity. The crude extract was successively fractionated into n-hexane, 85% aqueous methanol (85% aq.MeOH), n-butanol (n-BuOH), and water fractions by liquid- liquid partition. These include DPPH radical scavenging, hydroxyl radical scavenging in HT-1080 cells, peroxynitrite scavenging, and protective effect on DNA damage caused by hydroxyl radicals generated. In all assays, except for DPPH radical, 85% aq.MeOH and n-BuOH fraction showed the strong antioxidant activity. These results suggest that Z. japonica may be used as a potential source of natural antioxidants for the development of cosmetic product or functional food in the future.
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KEYWORD
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Zostera japonica, Reactive oxygen species (ROS), Peroxynitrite, DNA oxidation
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